rs1057519781
|
|
|
0.010 |
GeneticVariation |
BEFREE |
ALCL xenografts selected <i>in vivo</i> showed recurrent N1178H (5/10 mice) and G1269A (4/10 mice) mutations.
|
30322862 |
2018 |
rs1057519859
|
|
|
0.010 |
GeneticVariation |
BEFREE |
When OTX015 was associated with GANT61, a selective GLI1/2 inhibitor, C1156Y-resistant ALK ALCL growth was impaired.These findings support OTX015 clinical trials in refractory ALCL in combination with inhibitors of interleukin-2-inducible kinase or SHH/GLI1.
|
27793034 |
2016 |
rs113488022
|
|
|
0.010 |
GeneticVariation |
BEFREE |
An Immune Suppression-associated EBV-positive Anaplastic Large Cell Lymphoma With a BRAF V600E Mutation.
|
30320628 |
2019 |
rs113994089
|
|
|
0.010 |
GeneticVariation |
BEFREE |
These include novel variants with respect to ALK-fusion cancers, R1192P and T1151M, and with respect to ALCL, F1174L and I1171S.
|
27009859 |
2016 |
rs113994091
|
|
|
0.010 |
GeneticVariation |
BEFREE |
These include novel variants with respect to ALK-fusion cancers, R1192P and T1151M, and with respect to ALCL, F1174L and I1171S.
|
27009859 |
2016 |
rs121913377
|
|
|
0.010 |
GeneticVariation |
BEFREE |
An Immune Suppression-associated EBV-positive Anaplastic Large Cell Lymphoma With a BRAF V600E Mutation.
|
30320628 |
2019 |
rs1226137439
|
|
|
0.010 |
GeneticVariation |
BEFREE |
ALCL xenografts selected <i>in vivo</i> showed recurrent N1178H (5/10 mice) and G1269A (4/10 mice) mutations.
|
30322862 |
2018 |
rs201227909
|
|
|
0.010 |
GeneticVariation |
BEFREE |
ALCL xenografts selected <i>in vivo</i> showed recurrent N1178H (5/10 mice) and G1269A (4/10 mice) mutations.
|
30322862 |
2018 |
rs763830096
|
|
|
0.010 |
GeneticVariation |
BEFREE |
ALCL xenografts selected <i>in vivo</i> showed recurrent N1178H (5/10 mice) and G1269A (4/10 mice) mutations.
|
30322862 |
2018 |
rs863224686
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Methotrexate significantly induced apoptosis in ALK inhibitor-resistant cells expressing the NPM-ALK mutant harboring the point mutation, G262R, and in ALCL patient-derived NPM-ALK-positive Ki-JK cells.
|
31654627 |
2019 |